UNPARALLELED RESEARCH

Our ViraSuiteTM Platform Offers Endless Possibilities to Eradicate Disease

The Excision BioTherapeutics team includes some of the top biochemistry, chemistry and molecular biology experts with concentrations in the fields of retrovirology, virology, viral genetics, bioinformatics and advanced drug delivery.

Our research team is focused on developing gene editing therapeutics for life threatening viral-related diseases. Our objective is to rapidly advance each therapeutic into human clinical trials.

Our ViraSuiteTM platform areas of focus include:

  • Human Immunodeficiency Virus-1 Therapeutics
  • JC Virus and Progressive Multifocal Leukoencephalopathy
  • Herpes Simplex Virus 1 and 2 Therapeutics​
  • Hepatitis B Virus Therapeutics
  • Advanced DNA and Biologic Delivery Systems
  • Combinatorial methods of treatment in relation to existing Multiple Sclerosis medications

Excision Related Publications

Novel AIDS therapies based on gene editing
July 2017

In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models
May 2017

CRISPR Editing Technology in Biological and Biomedical Investigation
April 2017

Gene Editing Approaches against Viral Infections and Strategy to Prevent Occurrence of Viral Escape
December 2016

Negative Feedback Regulation of HIV-1 by Gene Editing Strategy
August 2016

Inhibition of HSV-1 Replication by Gene Editing Strategy
April 2016

Elimination of HIV-1 Genomes from Human T-lymphoid Cells by CRISPR/Cas9 Gene Editing
March 2016

CRISPR/gRNA-directed synergistic activation mediator (SAM) induces specific, persistent and robust reactivation of the HIV-1 latent reservoirs
November 2015

CRISPR/Cas9 System as an Agent for Eliminating Polyomavirus JC Infection
Sept 2015

Genome editing strategies: potential tools for eradicating HIV-1/AIDS
June 2015

Animal Models for Progressive Multifocal Leukoencephalopathy
May 2015

RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection
June 2014

The CRISPR/Cas9 genome editing methodology as a weapon against human viruses
April 2015